NAD+ Therapy

nad+ benefits

NAD+ Therapy | Spring & The Woodlands | Vitality Medical Clinic

Discover how NAD+ (nicotinamide adenine dinucleotide) supports energy metabolism, healthy aging, brain health, and cellular repair—with references to peer-reviewed studies.

What is NAD+?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme essential for cellular energy production, DNA repair, mitochondrial function, and healthy aging. Levels of NAD+ naturally decline with age, which may contribute to fatigue, metabolic dysfunction, and neurodegeneration.

Learn more about our NAD IV therapy services.

Health Benefits of NAD+

1. Energy & Mitochondrial Function

NAD+ is central to ATP production. Low NAD+ levels impair mitochondrial function, leading to reduced energy and increased oxidative stress.

2. Anti-Aging & DNA Repair

NAD+ fuels enzymes like sirtuins and PARPs that are vital for cellular stress resistance and DNA repair, linking it to longevity and healthy aging.

3. Brain Health & Cognition

Research shows NAD+ precursors may improve cerebral blood flow and cognitive function in older adults with mild cognitive impairment.

4. Cardiovascular Health

Clinical trials suggest NAD+ supplementation may support blood pressure regulation and vascular function.

Scientific Evidence

Human clinical studies demonstrate that NAD+ precursors such as nicotinamide riboside (NR) reliably increase circulating NAD+ metabolites within weeks. Exploratory studies suggest benefits for vascular aging, brain perfusion, and muscle metabolism.

See our full NAD+ research library.

Safety & Side Effects of NAD+ Therapy

Short-term human studies of NAD+ precursors report good tolerability. Mild side effects include nausea and digestive upset. High-dose safety and long-term outcomes are still under investigation.

FAQ

Does NAD+ decline with age?

Yes, studies show NAD+ levels decline with age across tissues, contributing to metabolic and neurological aging.

Is NAD+ therapy safe?

Short-term studies suggest safety, but long-term research is ongoing. Always consult a licensed healthcare provider.

References

  1. Verdin E. NAD+ in aging, metabolism, and neurodegeneration. Science. 2015. PubMed
  2. Covarrubias AJ, et al. NAD+ metabolism in cellular aging. Nat Rev Mol Cell Biol. 2021. Nature
  3. Martens CR, et al. NR supplementation boosts NAD+ in middle-aged adults. Nat Commun. 2018. Nature
  4. Orr ME, et al. NR in older adults with MCI. 2023. PMC
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